Louisville — Season 2021
Schedule and results
| Week | Date | Opponent | Loc | Result | Tickets |
|---|---|---|---|---|---|
| Week 1 | 09/07/2021 | Ole Miss | neutral | L 24-43 | — |
| Week 2 | 09/11/2021 | Eastern Kentucky | home | W 30-3 | — |
| Week 3 | 09/17/2021 | UCF | home | W 42-35 | — |
| Week 4 | 09/25/2021 | Florida State | away | W 31-23 | — |
| Week 5 | 10/02/2021 | Wake Forest | away | L 34-37 | — |
| Week 6 | 10/09/2021 | Virginia | home | L 33-34 | — |
| Week 8 | 10/23/2021 | Boston College | home | W 28-14 | — |
| Week 9 | 10/30/2021 | NC State | away | L 13-28 | — |
| Week 10 | 11/06/2021 | Clemson | home | L 24-30 | — |
| Week 11 | 11/13/2021 | Syracuse | home | W 41-3 | — |
| Week 12 | 11/19/2021 | Duke | away | W 62-22 | — |
| Week 13 | 11/28/2021 | Kentucky | home | L 21-52 | — |
| Post Season | 12/28/2021 | Air Force | neutral | L 28-31 | — |
Ticket links may include an affiliate ID.